ASTAGRAF XL Copay Card And Support Services

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Savings Information

ASTAGRAF XL Copay Card

With the ASTAGRAF XL Copay Card, patients pay as little as $0 for savings up to $3,000.* The ASTAGRAF XL Copay Card is valid for twelve (12) months from date of enrollment. Annual re-enrollment in the ASTAGRAF XL Copay Card Program is required.

Receiving the Card

Patients may receive the copay card in 1 of 2 ways:

  1. Directly from their healthcare provider
  2. Online at www.transplantmedsavings.com/extended
    • Eligible patients will be able to download and print a temporary card that can be activated immediately from the website
    • Subsequently, a copay card will be sent to the patient in the mail

Patients who receive their ASTAGRAF XL prescriptions by mail may be eligible to qualify for the ASTAGRAF XL Copay Card. Patients may utilize our mail-in option by filling out the “Mail Order” card within the ASTAGRAF XL Copay Card brochure or by visiting www.patientrebateonline.com.

  • Eligible participants in the ASTAGRAF XL Copay Card Program ("Program") may receive annual savings up to $3000 for ASTAGRAF XL. Patients must have prescription drug coverage for ASTAGRAF XL, however, this Program offer is not valid for patients whose prescription claims are reimbursed, in whole or in part, by any federal or state-government funded prescription drug benefit program including but not limited to Medicaid, Medicare, Medigap, Veterans Affairs (VA), Department of Defense (DoD), TRICARE, Puerto Rico Government Insurance, or any state patient or pharmaceutical assistance program. The ASTAGRAF XL Copay Card Program is valid for twelve (12) months from date of enrollment. Annual re-enrollment in the Program is required and subject to eligibility. Restrictions may apply. This offer is void where prohibited by law. Astellas reserves the right to rescind, revoke, or amend this offer without notice.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about ASTAGRAF XL?

ASTAGRAF XL can cause serious side effects, including:

  • Increased risk of cancer. People who take ASTAGRAF XL have an increased risk of getting some kinds of cancer, including skin and lymph gland cancer (lymphoma).
  • Increased risk of infection. ASTAGRAF XL is a medicine that affects your immune system. ASTAGRAF XL can lower the ability of your immune system to fight infections. Serious infections can happen in people receiving ASTAGRAF XL that can cause death. Call your healthcare provider right away if you have symptoms of an infection such as:
    • fever
    • sweats or chills
    • cough or flu-like symptoms
    • muscle aches
    • warm, red or painful areas on your skin
  • Increased risk of death in females who have had a liver transplant. You should not take ASTAGRAF XL if you have had a liver transplant without talking to your healthcare provider.

Who should not take ASTAGRAF XL?

Do not take ASTAGRAF XL if you are allergic to tacrolimus or any of the ingredients in ASTAGRAF XL.

Before you take ASTAGRAF XL tell your healthcare provider if you:

  • plan to receive any live vaccines.
  • have or have had liver, kidney or heart problems, or have any other medical conditions.
  • are pregnant or plan to become pregnant. ASTAGRAF XL may harm your unborn baby.
    • If you are able to become pregnant, you should use effective birth control before and during treatment with ASTAGRAF XL. Talk to your healthcare provider before starting treatment with ASTAGRAF XL about birth control methods that may be right for you.
    • Males who have female partners who are able to become pregnant should also use effective birth control before and during treatment with ASTAGRAF XL. Talk to your healthcare provider before starting treatment with ASTAGRAF XL about birth control methods that may be right for you.
  • are breastfeeding or plan to breastfeed. ASTAGRAF XL passes into your breast milk. You and your healthcare provider should decide if you will breastfeed while taking ASTAGRAF XL.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, natural, herbal or nutritional supplements. ASTAGRAF XL may affect the way other medicines work, and other medicines may affect how ASTAGRAF XL works.

How should I take ASTAGRAF XL?

  • Take ASTAGRAF XL exactly as your healthcare provider tells you to take it.
  • Your healthcare provider may change your dose if needed. Do not stop taking or change your dose of ASTAGRAF XL without talking to your healthcare provider.
  • Take ASTAGRAF XL capsules whole. Do not break, crush, chew or dissolve ASTAGRAF XL capsules before swallowing. If you cannot swallow ASTAGRAF XL capsules whole, tell your healthcare provider.
  • Take ASTAGRAF XL at the same time each morning, preferably on an empty stomach at least one hour before, or at least two hours after, you have eaten a meal.
  • If you miss your dose of ASTAGRAF XL, it should be taken as soon as possible, but no longer than 14 hours after your regularly scheduled time. If it is longer than 14 hours, the missed dose should be skipped and the next dose should be taken the following morning at your regularly scheduled time. Do not take two doses at the same time.
  • If you take too much ASTAGRAF XL, call your healthcare provider or go to the nearest hospital emergency room right away.

What should I avoid while taking ASTAGRAF XL?

  • Live vaccines such as flu vaccine through your nose, measles, mumps, rubella, polio by mouth, TB vaccine, yellow fever, chicken pox or typhoid.
  • Exposure to sunlight and UV light such as tanning machines. Wear protective clothing and use a sunscreen.
  • You should not eat grapefruit or drink grapefruit juice while taking ASTAGRAF XL.
  • You should not drink alcohol when taking ASTAGRAF XL.

What are the possible side effects of ASTAGRAF XL?
ASTAGRAF XL may cause serious side effects, including:

  • See “What is the most important information I should know about ASTAGRAF XL?"
  • Problems from medication errors such as graft rejection and other serious reactions. People who take ASTAGRAF XL have sometimes been given the wrong medicine, because some medicines have the same ingredient (tacrolimus) as ASTAGRAF XL. Serious reactions have happened including graft rejection. Check your ASTAGRAF XL when you get a new prescription to make sure you have received the right medicine.
    • Call your healthcare provider right away if you think you were given the wrong medicine
    • Ask your healthcare provider or pharmacist if you are not sure what ASTAGRAF XL should look like.
  • high blood sugar (diabetes). Your healthcare provider may do certain tests to check for diabetes. Call your healthcare provider right away if you have:
    • frequent urination
    • increased thirst or hunger
    • blurred vision
    • confusion
    • drowsiness
    • loss of appetite
    • fruity smell on your breath
    • nausea, vomiting, or stomach pain
  • kidney problems. Kidney problems are serious and common side effects of ASTAGRAF XL. Your healthcare provider may do certain tests to check your kidney function while you take ASTAGRAF XL.
  • nervous system problems. Nervous system problems are a serious and common side effect of ASTAGRAF XL. Call your healthcare provider or go to the nearest hospital emergency room right away if you get any of these symptoms while taking ASTAGRAF XL. These could be signs of serious nervous system problems:
    • confusion
    • changes in alertness
    • muscle tremors
    • numbness and tingling
    • headache
    • seizures
    • vision changes
  • high levels of potassium in your blood. Your healthcare provider may do certain tests to check your potassium level while you take ASTAGRAF XL.
  • high blood pressure. High blood pressure is a serious and common side effect of ASTAGRAF XL. Your healthcare provider will monitor your blood pressure and may ask you to check your blood pressure at home.
  • changes in the electrical activity of your heart (QT prolongation).
  • Severe low blood cell count (anemia).

The most common side effects of ASTAGRAF XL are diarrhea, constipation, nausea, swelling of the hands, ankles or legs, and tremors (shaking of the body).

These are not all the possible side effects of ASTAGRAF XL. For more information, ask your healthcare provider or pharmacist. Call your healthcare provider for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see the accompanying Medication Guide and full Prescribing Information, including Boxed Warning.